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September 19th, 2017, 06:24 PM #11Grand Member
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Re: Blood Thinners and Bruising from Shouldering a Rifle ?
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September 19th, 2017, 08:15 PM #12
Re: Blood Thinners and Bruising from Shouldering a Rifle ?
I'm no doctor. The OP prompted me to read this: https://www.consumerreports.org/cro/...some/index.htm
My read says that Effient is judged to be better suited for certain uses than Plavix, but does contain a black box warning about increased risk of hemorrhage. "Black Box" is the strongest labeling warning the FDA uses, so it's serious.
With regard to FDA agreeing to Effient's superiority claim, if Consumer Report has it right it is " For every 1,000 patients treated, it prevented 24 more heart attacks, strokes, and cardiovascular deaths than clopidogrel did, while it caused only 10 more cases of serious or fatal bleeding."
If one assumes that the "24 incidents" and the "10 incidents" are all equivalent in their impact on human life, then the net change is 14 incidents per 1,000 patient uses. A 1.4% difference. But I wouldn't be at all surprised to find it framed as a 41.6% decrease in negative outcomes to support a marketing claim.
That analysis may be garbage on my part, but it would be quite enough to be asking my interventional cardiologist a bunch of questions.
Even if (s)he isn't a firearms enthusiast.
JMO.
ETA: My own Plavix dose is 75mg/day as a lifetime maintenance dose, so it finally occurred to me that dosage matters. This may explain in part why I don't bruise at all when artillery shooting.
The studies are based on 300mg doses, normally in preparation for a procedure. In my case, my angina emergency instructions are to take (a few) nitro . . . if no help chew a whole aspirin and take 300mg of Plavix. And from what I read, I'd rather be on Plavix at that point than Effient because the next step might be bypass surgery, and I would rather not be on Effient.
Based on what I've read, I'll be asking my cardio whether that emergency dose should be 450mg or 600mg now, so thanks for bringing this up.
Again, JMO, but might be worthy of asking your cardio.Last edited by Twoboxer; September 19th, 2017 at 08:25 PM.
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September 20th, 2017, 01:02 PM #13
Re: Blood Thinners and Bruising from Shouldering a Rifle ?
You make a very good point about potential brain bleeding while taking blood thinners. A very close family friend suffered a major brain bleed a few weeks ago. He takes blood thinners for a heart condition and his doctors think that when he bumped his head a few weeks back, it caused his brain to hemorrhage. So far he's beaten the odds. They were able to save him and he is on his way to recovery; albeit a very long and slow one. Most people who suffer that sort of bleed do not survive.
I've been taking Xarelto for the past nine months for a blood clot behind my left knee. My Dr discovered it during an ultrasound a couple of weeks after I had leg surgery. So far, I haven't experienced any bleeding or bruising, but I am especially mindful of the potential.
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