See this thread:
http://www.pafoa.org/forum/question-...dly-force.html
The relevant statute:
http://members.aol.com/StatutesP8/18PA505.html
Quote:
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The use of deadly force is not justifiable under this section unless the actor believes that such force is necessary to protect himself against death, serious bodily injury, kidnapping or sexual intercourse compelled by force or threat; nor is it justifiable if...
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So basically you can use deadly force iff you reasonably fear death or serious bodily injury. In your home there is no duty to retreat. Shooting a gun at somebody is considered deadly force: do not "shoot to wound" if shooting to kill is not justified.
Oh yeah, and this is a biggie: Try your best to be familiar with the law and how it plays out in court. Minor things in what you do and say can have a major influence in the aftermath of a self-defense incident.